top of page


AMTZ
Travancore Heart Institute
Log In to Connect With Members
View and follow other members, leave comments & more.

Articles
Search
Pressure-Driven Microbubble Dynamics, Sanal Flow Choking, and Shock Fronts in Cryptogenic Intracerebral Hemorrhage
https://papers.ssrn.com/sol3/papers.cfm?abstract_id=5860469 Abstract Background: A proportion of intracerebral hemorrhage (ICH) occurs in individuals lacking hypertension, amyloid angiopathy, aneurysms, or identifiable vascular abnormalities, and the initiating biophysical events remain unclear. Fundamental bubble-physics studies show that heterogeneous nucleation can arise on microcrevice surfaces during pressure reduction [1], while acoustic bubble collapse can produce micr
Sanal Flow Choking in Cardiovascular Systems is Not a Scientific Fallacy but a Groundbreaking Concept Rooted in Cardiovascular Physiology
Indian J Thorac Cardiovasc Surg 2026 Apr;42(4):560-564. doi: 10.1007/s12055-024-01859-7. Epub 2024 Nov 21. https://link.springer.com/article/10.1007/s12055-024-01859-7
Decompression-Induced Microbubble Choking in Blood: Acoustic Softening, Sanal Flow Choking, and Spaceflight Implications
AIAA 2026-0720 Session: Humans in Space Logistics, Medical issues, Bio-Research Published Online:8 Jan 2026 https://doi.org/10.2514/6.2026-0720 https://arc.aiaa.org/doi/10.2514/6.2026-0720 Abstract: Decompression-induced microbubble nucleation and the resulting multiphase flow instability in blood pose a significant but underrecognized risk to cardiovascular stability during extravehicular activity (EVA), rapid cabin depressurization, and emergency re-pressurization. This stu
In vitro evidence of bubble-induced acoustic softening and Sanal flow choking in cardiovascular decompression
https://doi.org/10.1038/s41526-025-00517-5 npj Microgravity volume 11, Article number: 54 (2025) Published: 11 August 2025 https://www.nature.com/articles/s41526-025-00517-5 When astronauts or divers experience a rapid drop in surrounding pressure, tiny gas bubbles can form in their blood—a condition that can threaten heart and vessel function. In this study, we simulated such decompression using fresh, warmed blood samples (37–40 °C) placed in a vacuum chamber. Bubbles consi
PATIENT-SPECIFIC COMPUTATIONAL SIMULATION INCONGENITAL HEART DISEASE SURGERY: ADVANCED 3DRECONSTRUCTION, HAEMODYNAMIC MODELLING,COMPUTATIONAL FLUID DYNAMICS AND DIGITAL TWIN APPLICATIONS IN SVASD
DOI : 10.36106/paripex PARIPEX - INDIAN JOURNAL OF RESEARCH | Volume - 15 | Issue - 06 |June - 2026 | PRINT ISSN No. 2250 - 1991 https://www.worldwidejournals.com/paripex/recent_issues_pdf/2026/June/patientspecific-computational-simulation-in-congenital-heart-disease-surgery-advanced-3d-reconstruction-haemodynamic-modelling-computational-fluid-dynamics-and-digital_June_2026_7164780121_8401053.pdf Congenital heart disease (CHD) represents one of the most complex fields of card
Genomic Drivers in Cardiac Surgical Decision Making: From Molecular Mechanisms to Precision Operative Interventions
DOI:10.63363/aijfr.2026.v07i03.6551 June 2026 Advanced International Journal for Research 7(3) https://www.aijfr.com/papers/2026/3/6551.pdf The integration of genomic medicine into cardiac surgery represents a paradigm shift from traditional, size-based population metrics to patient-specific, gene-driven therapeutic strategies. Pathogenic variations in structural, contractile, and metabolic genes fundamentally dictate the natural history of cardiovascular diseases, altering v
HEMODYNAMIC DISSOCIATION AND REGIONALCOMPLIANCE FAILURE IN SEPARATED AORTICVALVE AND SUPRACORONARY ASCENDING AORTAREPLACEMENT: MECHANICS OF THE WHEATPROCEDURE
DOI : 10.36106/paripex PARIPEX - INDIAN JOURNAL OF RESEARCH | Volume - 15 | Issue - 09 |September - 2026 | PRINT ISSN No. 2250 - 1991 https://www.worldwidejournals.com/paripex/recent_issues_pdf/2026/September/hemodynamic-dissociation-and-regional-compliance-failure-in-separated-aortic-valve-and-supracoronary-ascending-aorta-replacement-mechanics-of-the-wheat-procedure_September_2026_7910310646_7400414.pdf The Wheat procedure serves as an alternative to composite graft root re
BIOMECHANICALALTERATIONS AND FLOW DYNAMICS OF THEINTERATRIAL SEPTUM FOLLOWING DEVICE AND PATCH CLOSURES:AN ADVANCED MATHEMATICAL, PHYSICAL, AND CLINICALINVESTIGATION
DOI : 10.36106/ijar Volume - 16 | Issue - 07 | July - 2026 | PRINT ISSN No. 2249 - 555X https://www.worldwidejournals.com/indian-journal-of-applied-research-(IJAR)/fileview/biomechanical-alterations-and-flow-dynamics-of-the-interatrial-septum-following-device-and-patch-closures-an-advanced-mathematical-physical-and-clinical-investigation_July_2026_0889412017_8703934.pdf Objective: The interatrial septum (IAS) is a highly specialized, compliant cardiac structure that modulates
OPTOGENETIC TERMINATION OF RE-ENTRANT ARRHYTHMIAS: ACOMPREHENSIVE ANALYSIS
https://www.worldwidejournals.com/global-journal-for-research-analysis-GJRA/recent_issues_pdf/2026/September/optogenetic-termination-of-reentrant-arrhythmias-a-comprehensive-analysis_September_2026_0041698147_3900790.pdf DOI : 10.36106/gjra VOLUME - 15, ISSUE - 09, SEPTEMBER - 2026 • PRINT ISSN No. 2277 - 8160 Malignant cardiac tachyarrhythmias, such as ventriculartachycardia (VT) and atrial fibrillation (AF), represent leadingcauses of global mortality and morbidity. These l
ANOMALOUS LEFT MAIN CORONARY ARTERIES ARISING FROM THE RIGHTSINUS OF VALSALVA WITH A PREPULMONIC COURSE: EMBRYOLOGICALINSIGHTS, GEOMETRIC HAZARDS IN INTERVENTIONAL CARDIOLOGY,ADVANCED FLUID DYNAMICS
VOLUME - 15, ISSUE - 08, AUGUST - 2026 • PRINT ISSN No. 2277 - 8160 • DOI : 10.36106/gjra https://www.worldwidejournals.com/global-journal-for-research-analysis-GJRA/file.php?val=anomalous-left-main-coronary-arteries-arising-from-the-right-sinus-of-valsalva-with-a-prepulmonic-course-embryological-insights-geometric-hazards-in-interventional-cardiology_August_2026_8954746715_3505684.pdf Anomalous aortic origin of a coronary artery (AAOCA), specifically the anomalous left main
ADVANCED FLUID DYNAMICS, MECHANICS, AND HYDRODYNAMIC EFFICIENCY OF PULMONARY ARTERY BANDING IN CONGENITAL HEART LESIONS: A CONTEMPORARY FRAMEWORK FOR PRECISION PALLIATION
VOLUME - 15, ISSUE - 08, AUGUST - 2026 • PRINT ISSN No. 2277 - 8160 • DOI : 10.36106/gjra Pulmonary artery banding (PAB) has evolved from a historic, non-specific palliative measure to a highly sophisticated, hemodynamically engineered intervention. This article delineates the advanced fluid dynamics, classical mechanics, and mathematical governing equations underlying the operation of a physical constriction within the main pulmonary trunk. We present a novel, future-oriente
PATHOPHYSIOLOGY, SURGICAL STRATEGIES, AND ADVANCEDPERIOPERATIVE MANAGEMENT OF LATE DEVICE EXPLANTATION FORLEFT BUNDLE BRANCH BLOCK AND LEFT VENTRICULAR DYSFUNCTION FOLLOWING TRANSCATHETER VSD CLOSURE
Transcatheter device closure of ventricular septal defects (VSDs) has emerged as an alternative to surgical repair. However, its proximity to the cardiac conduction system can induce delayed electrical and mechanical complications. This article reviews the anatomical and mechanical pressure causations of late-onset Left Bundle Branch Block (LBBB) and subsequent Left Ventricular (LV) dysfunction following perimembranous VSD device deployment. We examine the biophysical pathway
PRADEEP'S THREE FUNDAMENTAL LAWS OF CARDIAC SURGERY: A UNIFIEDMATHEMATICAL, HEMODYNAMIC, AND BIOPHYSICAL FRAMEWORK FORMODERN CARDIOVASCULAR INTERVENTION
https://www.doi.org/10.36106/gjra PDF- https://www.worldwidejournals.com/global-journal-for-research-analysis-GJRA/file.php?val=pradeeps-three-fundamental-laws-of-cardiac-surgery-a-unified-mathematical-hemodynamic-and-biophysical-framework-for-modern-cardiovascular-intervention_June_2026_7821081102_8401269.pdf Cardiac surgery represents one of the most advanced integrations of physiology, biomechanics, uid dynamics, thermodynamics, and bioengineering in modern medicine. Desp
PRADEEP'S THE THREE FUNDAMENTAL LAWS OF CARDIACSURGERY: FLOW, STRUCTURE, AND PROTECTION AS AUNIFIED PHYSIOLOGICAL FRAMEWORK FOR MODERNCARDIOVASCULAR INTERVENTION-THE LAW OF FLOWTHE PERFUSION MANDATE
https://www.doi.org/10.36106/paripex PDF- https://www.worldwidejournals.com/paripex/recent_issues_pdf/2026/June/pradeeps-the-three-fundamental-laws-of-cardiac-surgery-flow-structure-and-protection-as-a-unified-physiological-framework-for-modern-cardiovascular-interventionthe-law-of-flow-the-perfusion-mandate_June_2026_1120418676_7400697.pdf Cardiac surgery has evolved into a highly sophisticated discipline integrating physiology, biomechanics, molecular biology, perfusion sci
THE DYNATOME CLASSIFICATION SYSTEM:NEW INNOVATIVE FUNCTIONAL SCORING OFBICUSPID AORTIC VALVE FOR CARDIACINTERVENTIONS
PARIPEX - INDIAN JOURNAL F RESEARCH | O March - 202 Volume - 15 | Issue - 03 | 6 | PRINT ISSN No. 2250 - 1991 DOI : 10.36106/paripex ABSTRACT - Cardiovascular diseases (CVDs) remain the leading cause of global mortality. Traditional 2D cardiomyocyte cultures and animal models fail to fully replicate human-specific cardiac morphogenesis, electrophysiology, and drug responses. Cardiac organoids (COs), including self-organizing cardioids, represent a transformative 3D in vitro s
CARDIAC ORGANOIDS - ADVANCED PLATFORMS FOR DISEASE MODELLING,DRUG SCREENING, AND TRANSLATIONAL CARDIAC REGENERATION
VOLUME - 15, ISSUE - 03, MARCH - 2026 • PRINT ISSN No. 2277 - 8160 DOI : 10.36106/gjra ABSTRACT - Cardiovascular diseases (CVDs) remain the leading cause of global mortality. Traditional 2D cardiomyocyte cultures and animal models fail to fully replicate human-specific cardiac morphogenesis, electrophysiology, and drug responses. Cardiac organoids (COs), including self-organizing cardioids, represent a transformative 3D in vitro system capable of recapitulating chamber morpho
Heart as an Inverted Octagonal Pyramid: Fluid Dynamics of Cardiac Ejection
https://doi.org/10.11648/j.ijcts.20251103.11
A FRESH LOOK AT HALF-TURNED TRUNCAL SWITCH OPERATION (HTTSO)
https://www.academia.edu/129155951/A_FRESH_LOOK_AT_HALF_TURNED_TRUNCAL_SWITCH_OPERATION_HTTSO?source=swp_share
EMBRYOLOGICAL CARDIAC LOOPING: FROM GENETIC BLUEPRINTS TO BIOENGINEERING HORIZONS A COMPREHENSIVE REVIEW OF MECHANISMS, MODELS, AND THERAPEUTIC PROSPECTS
https://www.academia.edu/129155915/EMBRYOLOGICAL_CARDIAC_LOOPING_FROM_GENETIC_BLUEPRINTS_TO_BIOENGINEERING_HORIZONS_A_COMPREHENSIVE_REVIE...
3D Bioprinting Techniques for Cardiac Fabrication: A comprehensive Analysis of Current Methods, Feasibility for Total Artificial Heart (TAH) Development, and Future Technological Horizons
Published in Trivandrum Medical College Alumni Association Annals - Grand 20 - 2025 March Link
bottom of page